The goal of my lab is to understand the molecular events that govern the development of specific organs. In particular, we are interested in the early development of the cardiovascular system, the lung and thyroid. We have found that retinoic acid is a critical signaling molecule in controlling the decisions regarding the differentiation of these organ systems. We are also trying to understand the cellular events that govern the morphogenesis of the organ.

We utilize a combination of classical embryology, molecular biology and genome manipulation to look at these challenging questions.