Dr. Zhang graduated at Zhongshan University in China and late received his PhD degree from Karolinska Institute, Sweden in 1997. He finished his postdoctoral training in the Department of Pathology, University of Toronto in 2003. He is currently a professor in the Department of Medicine and the Department of Pathology at Western University. His laboratory is at the Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre. His research interest is focused on the mechanisms of immune regulation and tolerance. He and his colleagues have identified a novel type of regulatory T cells, double negative (DN-Treg) cells, that can suppress immune responses and prolong graft survival. In addition, his team has found that NK cells can mediate ischemia reperfusion injury and chronic rejection in transplantation. Recently, Dr. Zhang and colleagues were the first to describe the contribution of necroptosis in transplantation. Currently, there are two areas under active investigation in his laboratory: i) the mechanism of cell death pathways-mediated tissue injury and its effects on permitting tolerance induction in transplantation, and ii) the roles of NK and T cells in immune tolerance. He is a member of AST, CST and AAI. His research has been supported by CIHR, CDTRP, HSF and KFOC.